Medications for Initial and Continued Treatment of OUD
- All medications above have been shown to reduce cravings for opioids, recurrence, and opioid overdose in large clinical trials.
- These medications also help retain people in treatment and decrease illegal opioid use and property crime.
- The NIH HEAL Initiative has resources to help explain what the forms of medications for OUD are and how they help.
- Because opioid addiction is a chronic disease like heart disease or diabetes, it can require medication for many years or even for life.
- Prematurely stopping medication for OUD can quickly lead to recurrence, overdose, and death.
|TABLE 3. THREE FORMS OF FDA-APPROVED MEDICATION FOR OUD|
|MECHANISM OF ACTION||Full opioid agonist||Partial opioid agonist||Opioid antagonist|
|DELIVERY||Oral||Sublingual film, injection||Injection|
|SETTING||Licensed OTP that can provide services in a criminal justice system (CJS) setting||CJS, primary care, specialty care setting (X-waiver DEA: MD with 8 hours training; PA/NP with 24 hours training)||CJS, primary care, specialty care setting (no special licensing)|